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Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

BACKGROUND: Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuins, which are homologs of the yeast Sir2 gene. SIRT3 is the only sirtuin with a reported association with the human life span. Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) plays important roles in adaptive ther...

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Detalles Bibliográficos
Autores principales:	Kong, Xingxing, Wang, Rui, Xue, Yuan, Liu, Xiaojun, Zhang, Huabing, Chen, Yong, Fang, Fude, Chang, Yongsheng
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908542/ https://www.ncbi.nlm.nih.gov/pubmed/20661474 http://dx.doi.org/10.1371/journal.pone.0011707

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