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Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study

BACKGROUND: Probiotic bacteria are suggested to play a role in the maintenance of oral health. Such health promoting bacteria are added to different commercial probiotic products. The aim of the study was to investigate the ability of a selection of lactobacilli strains, used in commercially availab...

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Autores principales: Hasslöf, Pamela, Hedberg, Maria, Twetman, Svante, Stecksén-Blicks, Christina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908555/
https://www.ncbi.nlm.nih.gov/pubmed/20598145
http://dx.doi.org/10.1186/1472-6831-10-18
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author Hasslöf, Pamela
Hedberg, Maria
Twetman, Svante
Stecksén-Blicks, Christina
author_facet Hasslöf, Pamela
Hedberg, Maria
Twetman, Svante
Stecksén-Blicks, Christina
author_sort Hasslöf, Pamela
collection PubMed
description BACKGROUND: Probiotic bacteria are suggested to play a role in the maintenance of oral health. Such health promoting bacteria are added to different commercial probiotic products. The aim of the study was to investigate the ability of a selection of lactobacilli strains, used in commercially available probiotic products, to inhibit growth of oral mutans streptococci and C. albicans in vitro. METHODS: Eight probiotic lactobacilli strains were tested for growth inhibition on three reference strains and two clinical isolates of mutans streptococci as well as two reference strains and three clinical isolates of Candida albicans with an agar overlay method. RESULTS: At concentrations ranging from 10(9 )to 10(5 )CFU/ml, all lactobacilli strains inhibited the growth of the mutans streptococci completely with the exception of L. acidophilus La5 that executed only a slight inhibition of some strains at concentrations corresponding to 10(7 )and 10(5 )CFU/ml. At the lowest cell concentration (10(3 )CFU/ml), only L. plantarum 299v and L. plantarum 931 displayed a total growth inhibition while a slight inhibition was seen for all five mutans streptococci strains by L. rhamnosus LB21, L. paracasei F19, L. reuteri PTA 5289 and L. reuteri ATCC 55730. All the tested lactobacilli strains reduced candida growth but the effect was generally weaker than for mutans streptococci. The two L. plantarum strains and L. reuteri ATCC 55730 displayed the strongest inhibition on Candida albicans. No significant differences were observed between the reference strains and the clinical isolates. CONCLUSION: The selected probiotic strains showed a significant but somewhat varying ability to inhibit growth of oral mutans streptococci and Candida albicans in vitro.
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spelling pubmed-29085552010-07-23 Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study Hasslöf, Pamela Hedberg, Maria Twetman, Svante Stecksén-Blicks, Christina BMC Oral Health Research Article BACKGROUND: Probiotic bacteria are suggested to play a role in the maintenance of oral health. Such health promoting bacteria are added to different commercial probiotic products. The aim of the study was to investigate the ability of a selection of lactobacilli strains, used in commercially available probiotic products, to inhibit growth of oral mutans streptococci and C. albicans in vitro. METHODS: Eight probiotic lactobacilli strains were tested for growth inhibition on three reference strains and two clinical isolates of mutans streptococci as well as two reference strains and three clinical isolates of Candida albicans with an agar overlay method. RESULTS: At concentrations ranging from 10(9 )to 10(5 )CFU/ml, all lactobacilli strains inhibited the growth of the mutans streptococci completely with the exception of L. acidophilus La5 that executed only a slight inhibition of some strains at concentrations corresponding to 10(7 )and 10(5 )CFU/ml. At the lowest cell concentration (10(3 )CFU/ml), only L. plantarum 299v and L. plantarum 931 displayed a total growth inhibition while a slight inhibition was seen for all five mutans streptococci strains by L. rhamnosus LB21, L. paracasei F19, L. reuteri PTA 5289 and L. reuteri ATCC 55730. All the tested lactobacilli strains reduced candida growth but the effect was generally weaker than for mutans streptococci. The two L. plantarum strains and L. reuteri ATCC 55730 displayed the strongest inhibition on Candida albicans. No significant differences were observed between the reference strains and the clinical isolates. CONCLUSION: The selected probiotic strains showed a significant but somewhat varying ability to inhibit growth of oral mutans streptococci and Candida albicans in vitro. BioMed Central 2010-07-02 /pmc/articles/PMC2908555/ /pubmed/20598145 http://dx.doi.org/10.1186/1472-6831-10-18 Text en Copyright ©2010 Hasslöf et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hasslöf, Pamela
Hedberg, Maria
Twetman, Svante
Stecksén-Blicks, Christina
Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title_full Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title_fullStr Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title_full_unstemmed Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title_short Growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
title_sort growth inhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli - an in vitro study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908555/
https://www.ncbi.nlm.nih.gov/pubmed/20598145
http://dx.doi.org/10.1186/1472-6831-10-18
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