Structural Maintenance of Chromosomes (SMC) Proteins Promote Homolog-Independent Recombination Repair in Meiosis Crucial for Germ Cell Genomic Stability

In meiosis, programmed DNA breaks repaired by homologous recombination (HR) can be processed into inter-homolog crossovers that promote the accurate segregation of chromosomes. In general, more programmed DNA double-strand breaks (DSBs) are formed than the number of inter-homolog crossovers, and the...

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Detalles Bibliográficos
Autores principales: Bickel, Jeremy S., Chen, Liting, Hayward, Jin, Yeap, Szu Ling, Alkers, Ashley E., Chan, Raymond C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908675/
https://www.ncbi.nlm.nih.gov/pubmed/20661436
http://dx.doi.org/10.1371/journal.pgen.1001028

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