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T-Cell Lymphoma Presenting as Painful Ophthalmoplegia

PURPOSE: To present a case of peripheral T-cell lymphoma presenting as painful ophthalmoplegia. METHODS: A 61-year-old woman presented with a 2-week history of headache and eyeball pain. Examination showed mild exophthalmos, complete ophthalmoplegia, and ptosis of the left eye. Under the impression...

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Autores principales: Lee, Dong Sub, Woo, Kyung In, Chang, Hae Ran
Formato: Texto
Lenguaje:English
Publicado: The Korean Ophthalmological Society 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908846/
https://www.ncbi.nlm.nih.gov/pubmed/17004636
http://dx.doi.org/10.3341/kjo.2006.20.3.192
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author Lee, Dong Sub
Woo, Kyung In
Chang, Hae Ran
author_facet Lee, Dong Sub
Woo, Kyung In
Chang, Hae Ran
author_sort Lee, Dong Sub
collection PubMed
description PURPOSE: To present a case of peripheral T-cell lymphoma presenting as painful ophthalmoplegia. METHODS: A 61-year-old woman presented with a 2-week history of headache and eyeball pain. Examination showed mild exophthalmos, complete ophthalmoplegia, and ptosis of the left eye. Under the impression of nonspecific orbital inflammation, she was treated with oral prednisone with initial response. Two months later, she revisited the clinic with exacerbated symptoms. Anterior orbitotomy and incisional biopsy was performed for the inferior rectus muscle lesion. RESULTS: Histopathologic examination revealed an infiltrate of atypical lymphoid cells between degenerative muscle bundles. It was consistent with peripheral T-cell lymphoma. A metastatic workup was performed without any evidence of extraorbital tumor. The patient was recommended to be treated with chemotherapy, however, refused to take the treatment. The patient died of progression of the disease in a month. CONCLUSIONS: T-cell lymphoma in the orbit can present as painful ophthalmoplegia and take a rapid clinical course. The disease should be regarded as one of the differential diagnosis for painful ophthalmoplegia refractory to corticosteroid therapy.
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spelling pubmed-29088462010-07-28 T-Cell Lymphoma Presenting as Painful Ophthalmoplegia Lee, Dong Sub Woo, Kyung In Chang, Hae Ran Korean J Ophthalmol Case Report PURPOSE: To present a case of peripheral T-cell lymphoma presenting as painful ophthalmoplegia. METHODS: A 61-year-old woman presented with a 2-week history of headache and eyeball pain. Examination showed mild exophthalmos, complete ophthalmoplegia, and ptosis of the left eye. Under the impression of nonspecific orbital inflammation, she was treated with oral prednisone with initial response. Two months later, she revisited the clinic with exacerbated symptoms. Anterior orbitotomy and incisional biopsy was performed for the inferior rectus muscle lesion. RESULTS: Histopathologic examination revealed an infiltrate of atypical lymphoid cells between degenerative muscle bundles. It was consistent with peripheral T-cell lymphoma. A metastatic workup was performed without any evidence of extraorbital tumor. The patient was recommended to be treated with chemotherapy, however, refused to take the treatment. The patient died of progression of the disease in a month. CONCLUSIONS: T-cell lymphoma in the orbit can present as painful ophthalmoplegia and take a rapid clinical course. The disease should be regarded as one of the differential diagnosis for painful ophthalmoplegia refractory to corticosteroid therapy. The Korean Ophthalmological Society 2006-09 2006-09-30 /pmc/articles/PMC2908846/ /pubmed/17004636 http://dx.doi.org/10.3341/kjo.2006.20.3.192 Text en Copyright © 2006 by the Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Dong Sub
Woo, Kyung In
Chang, Hae Ran
T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title_full T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title_fullStr T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title_full_unstemmed T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title_short T-Cell Lymphoma Presenting as Painful Ophthalmoplegia
title_sort t-cell lymphoma presenting as painful ophthalmoplegia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908846/
https://www.ncbi.nlm.nih.gov/pubmed/17004636
http://dx.doi.org/10.3341/kjo.2006.20.3.192
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