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Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance
One of the greatest challenges facing the pharmaceutical industry today is the failure of promising new drug candidates due to unanticipated adverse effects discovered during preclinical animal safety studies and clinical trials. Late stage attrition increases the time required to bring a new drug t...
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| Formato: | Texto |
| Lenguaje: | English |
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Bentham Science Publishers Ltd
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908937/ https://www.ncbi.nlm.nih.gov/pubmed/20053163 http://dx.doi.org/10.2174/138620710790596736 |