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Nef-specific CD45RA+ CD8+ T cells secreting MIP-1β but not IFN-γ are associated with nonprogressive HIV-1 infection

BACKGROUND: Long-term survival of HIV-1 infected individuals is usually achieved by continuous administration of combination antiretroviral therapy (ART). An exception to this scenario is represented by HIV-1 infected nonprogressors (NP) which maintain relatively high circulating CD4+ T cells withou...

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Detalles Bibliográficos
Autores principales: Dembek, Claudia J, Kutscher, Sarah, Heltai, Silvia, Allgayer, Simone, Biswas, Priscilla, Ghezzi, Silvia, Vicenzi, Elisa, Hoffmann, Dieter, Reitmeir, Peter, Tambussi, Giuseppe, Bogner, Johannes R, Lusso, Paolo, Stellbrink, Hans-J, Santagostino, Elena, Vollbrecht, Thomas, Goebel, Frank D, Protzer, Ulrike, Draenert, Rika, Tinelli, Marco, Poli, Guido, Erfle, Volker, Malnati, Mauro, Cosma, Antonio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909146/
https://www.ncbi.nlm.nih.gov/pubmed/20598119
http://dx.doi.org/10.1186/1742-6405-7-20