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Monotonicity, frustration, and ordered response: an analysis of the energy landscape of perturbed large-scale biological networks
BACKGROUND: For large-scale biological networks represented as signed graphs, the index of frustration measures how far a network is from a monotone system, i.e., how incoherently the system responds to perturbations. RESULTS: In this paper we find that the frustration is systematically lower in tra...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909160/ https://www.ncbi.nlm.nih.gov/pubmed/20537143 http://dx.doi.org/10.1186/1752-0509-4-83 |