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Role of the ATM-Checkpoint Kinase 2 Pathway in CDT-Mediated Apoptosis of Gingival Epithelial Cells

The cytolethal distending toxin (CDT) of the oral pathogen Aggregatibacter actinomycetemcomitans induces cell cycle arrest and apoptosis in various cell types. Western analysis, pharmacological inhibition and siRNA silencing were performed in human immortalized gingival keratinocytes (HIGK) to disse...

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Detalles Bibliográficos
Autores principales:	Alaoui-El-Azher, Mounia, Mans, Jeffrey J., Baker, Henry V., Chen, Casey, Progulske-Fox, Ann, Lamont, Richard J., Handfield, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909199/ https://www.ncbi.nlm.nih.gov/pubmed/20668524 http://dx.doi.org/10.1371/journal.pone.0011714

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