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Defining the Functional Domain of Programmed Cell Death 10 through Its Interactions with Phosphatidylinositol-3,4,5-Trisphosphate

Cerebral cavernous malformations (CCM) are vascular abnormalities of the central nervous system predisposing blood vessels to leakage, leading to hemorrhagic stroke. Three genes, Krit1 (CCM1), OSM (CCM2), and PDCD10 (CCM3) are involved in CCM development. PDCD10 binds specifically to PtdIns(3,4,5)P3...

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Detalles Bibliográficos
Autores principales:	Dibble, Christopher F., Horst, Jeremy A., Malone, Michael H., Park, Kun, Temple, Brenda, Cheeseman, Holly, Barbaro, Justin R., Johnson, Gary L., Bencharit, Sompop
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909203/ https://www.ncbi.nlm.nih.gov/pubmed/20668527 http://dx.doi.org/10.1371/journal.pone.0011740

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