Cargando…

Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

BACKGROUND: Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate due to evaluation of multiple individual clinical outco...

Descripción completa

Detalles Bibliográficos
Autores principales: Pogue, Janice, Thabane, Lehana, Devereaux, PJ, Yusuf, Salim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909251/
https://www.ncbi.nlm.nih.gov/pubmed/20529275
http://dx.doi.org/10.1186/1471-2288-10-49