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Testing for heterogeneity among the components of a binary composite outcome in a clinical trial
BACKGROUND: Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate due to evaluation of multiple individual clinical outco...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909251/ https://www.ncbi.nlm.nih.gov/pubmed/20529275 http://dx.doi.org/10.1186/1471-2288-10-49 |