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Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

BACKGROUND: Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate due to evaluation of multiple individual clinical outco...

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Detalles Bibliográficos
Autores principales:	Pogue, Janice, Thabane, Lehana, Devereaux, PJ, Yusuf, Salim
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909251/ https://www.ncbi.nlm.nih.gov/pubmed/20529275 http://dx.doi.org/10.1186/1471-2288-10-49

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