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Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans

Salivary histatin 5 (Hst 5) is a cationic salivary protein with high fungicidal activity against Candida albicans. Binding to the cell wall followed by intracellular translocation is required for killing; however, specific binding components and critical toxic events are not understood. In this stud...

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Detalles Bibliográficos
Autores principales: Jang, Woong Sik, Bajwa, Jashanjot Singh, Sun, Jianing N, Edgerton, Mira
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909388/
https://www.ncbi.nlm.nih.gov/pubmed/20487276
http://dx.doi.org/10.1111/j.1365-2958.2010.07210.x