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IL-18, but not IL-15, contributes to the IL-12-dependent induction of NK-cell effector functions by Leishmania infantum in vivo

Activation of NK cells is a hallmark of infections with intracellular pathogens. We previously showed that the protozoan parasite Leishmania infantum triggered a rapid NK-cell response in mice that required TLR9-positive myeloid DC and IL-12, but no IFN-α/β. Here, we investigated whether IL-15 or IL...

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Detalles Bibliográficos
Autores principales:	Haeberlein, Simone, Sebald, Heidi, Bogdan, Christian, Schleicher, Ulrike
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2010
Materias:	Immunity to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909391/ https://www.ncbi.nlm.nih.gov/pubmed/20213736 http://dx.doi.org/10.1002/eji.200939988

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