Cargando…

Ligand dimensions are important in controlling NK-cell responses

Size-dependent protein segregation at the cell–cell contact interface has been suggested to be critical for regulation of lymphocyte function. We investigated the role of ligand dimensions in regulation of mouse NK-cell activation and inhibition. Elongated forms of H60a, a mouse NKG2D ligand, were g...

Descripción completa

Detalles Bibliográficos
Autores principales: Brzostek, Joanna, Chai, Jian-Guo, Gebhardt, Friedemann, Busch, Dirk H, Zhao, Rui, van der Merwe, P Anton, Gould, Keith G
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909396/
https://www.ncbi.nlm.nih.gov/pubmed/20432238
http://dx.doi.org/10.1002/eji.201040335