Cargando…
Ligand dimensions are important in controlling NK-cell responses
Size-dependent protein segregation at the cell–cell contact interface has been suggested to be critical for regulation of lymphocyte function. We investigated the role of ligand dimensions in regulation of mouse NK-cell activation and inhibition. Elongated forms of H60a, a mouse NKG2D ligand, were g...
Autores principales: | Brzostek, Joanna, Chai, Jian-Guo, Gebhardt, Friedemann, Busch, Dirk H, Zhao, Rui, van der Merwe, P Anton, Gould, Keith G |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909396/ https://www.ncbi.nlm.nih.gov/pubmed/20432238 http://dx.doi.org/10.1002/eji.201040335 |
Ejemplares similares
-
Costimulation of IL-2 Production through CD28 Is Dependent on the Size of Its Ligand
por: Lim, Hong-Sheng, et al.
Publicado: (2015) -
Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition
por: Brzostek, Joanna, et al.
Publicado: (2016) -
Nanoscale Colocalization of NK Cell Activating and Inhibitory Receptors Controls Signal Integration
por: Tomaz, David, et al.
Publicado: (2022) -
Structural Basis for Recognition of Cellular and Viral Ligands by NK Cell Receptors
por: Li, Yili, et al.
Publicado: (2014) -
Editorial: Tailoring NK Cell Receptor–Ligand Interactions: An Art in Evolution
por: Koehl, Ulrike, et al.
Publicado: (2018)