Leishmania donovani-induced expression of signal regulatory protein α on Kupffer cells enhances hepatic invariant NKT-cell activation

Signal regulatory protein α (SIRPα) and its cognate ligand CD47 have been documented to have a broad range of cellular functions in development and immunity. Here, we investigated the role of SIRPα–CD47 signalling in invariant NKT (iNKT) cell responses. We found that CD47 was required for the optima...

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Detalles Bibliográficos
Autores principales: Beattie, Lynette, Svensson, Mattias, Bune, Alison, Brown, Najmeeyah, Maroof, Asher, Zubairi, Soombul, Smith, Katharine R, Kaye, Paul M
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Immunity to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909397/
https://www.ncbi.nlm.nih.gov/pubmed/19877019
http://dx.doi.org/10.1002/eji.200939863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909397/
https://www.ncbi.nlm.nih.gov/pubmed/19877019
http://dx.doi.org/10.1002/eji.200939863

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