BASOPHILS AND THE T HELPER 2 ENVIRONMENT CAN PROMOTE THE DEVELOPMENT OF LUPUS NEPHRITIS

In systemic lupus erythematosus (SLE) self-reactive antibodies can target the kidney (lupus nephritis) leading to functional failure and possible mortality. We report that activation of basophils by autoreactive IgE, causes their homing to lymph nodes, promoting T(H)2 cell differentiation, and enhan...

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Detalles Bibliográficos
Autores principales: Charles, Nicolas, Hardwick, Donna, Daugas, Eric, Illei, Gabor G., Rivera, Juan
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909583/
https://www.ncbi.nlm.nih.gov/pubmed/20512127
http://dx.doi.org/10.1038/nm.2159

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