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Role of NAD(P)H Oxidase in Superoxide Generation and Endothelial Dysfunction in Goto-Kakizaki (GK) Rats as a Model of Nonobese NIDDM
BACKGROUND: Cardiovascular disease is the leading cause of mortality in diabetics, and it has a complex etiology that operates on several levels. Endothelial dysfunction and increased generation of reactive oxygen species are believed to be an underlying cause of vascular dysfunction and coronary ar...
Autores principales: | Gupte, Sachin, Labinskyy, Nazar, Gupte, Rakhee, Csiszar, Anna, Ungvari, Zoltan, Edwards, John G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909910/ https://www.ncbi.nlm.nih.gov/pubmed/20668682 http://dx.doi.org/10.1371/journal.pone.0011800 |
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