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A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) productively infects only humans and chimpanzees but not Old World monkeys, such as rhesus and cynomolgus (CM) monkeys. To establish a monkey model of HIV-1/AIDS, several HIV-1 derivatives have been constructed. We previously reported that effi...

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Detalles Bibliográficos
Autores principales: Kuroishi, Ayumu, Bozek, Katarzyna, Shioda, Tatsuo, Nakayama, Emi E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910007/
https://www.ncbi.nlm.nih.gov/pubmed/20609213
http://dx.doi.org/10.1186/1742-4690-7-58