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Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays

BACKGROUND: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique way on each chip. It is likely that such artifacts affect many SNP arrays, but the normalization methods used in currently...

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Detalles Bibliográficos
Autores principales: Chai, High Seng, Therneau, Terry M, Bailey, Kent R, Kocher, Jean-Pierre A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910027/
https://www.ncbi.nlm.nih.gov/pubmed/20587065
http://dx.doi.org/10.1186/1471-2105-11-356