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Efficient inhibition of miR-155 function in vivo by peptide nucleic acids
MicroRNAs (miRNAs) play an important role in diverse physiological processes and are potential therapeutic agents. Synthetic oligonucleotides (ONs) of different chemistries have proven successful for blocking miRNA expression. However, their specificity and efficiency have not been fully evaluated....
Autores principales: | Fabani, Martin M., Abreu-Goodger, Cei, Williams, Donna, Lyons, Paul A., Torres, Adrian G., Smith, Kenneth G. C., Enright, Anton J., Gait, Michael J., Vigorito, Elena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910044/ https://www.ncbi.nlm.nih.gov/pubmed/20223773 http://dx.doi.org/10.1093/nar/gkq160 |
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