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Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

MicroRNAs (miRNAs) play an important role in diverse physiological processes and are potential therapeutic agents. Synthetic oligonucleotides (ONs) of different chemistries have proven successful for blocking miRNA expression. However, their specificity and efficiency have not been fully evaluated....

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Detalles Bibliográficos
Autores principales: Fabani, Martin M., Abreu-Goodger, Cei, Williams, Donna, Lyons, Paul A., Torres, Adrian G., Smith, Kenneth G. C., Enright, Anton J., Gait, Michael J., Vigorito, Elena
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910044/
https://www.ncbi.nlm.nih.gov/pubmed/20223773
http://dx.doi.org/10.1093/nar/gkq160

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