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Visualizing helicases unwinding DNA at the single molecule level

DNA helicases are motor proteins that catalyze the unwinding of double-stranded DNA into single-stranded DNA using the free energy from ATP hydrolysis. Single molecule approaches enable us to address detailed mechanistic questions about how such enzymes move processively along DNA. Here, an optical...

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Detalles Bibliográficos
Autores principales:	Fili, Natali, Mashanov, Gregory I., Toseland, Christopher P., Batters, Christopher, Wallace, Mark I., Yeeles, Joseph T. P., Dillingham, Mark S., Webb, Martin R., Molloy, Justin E.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910053/ https://www.ncbi.nlm.nih.gov/pubmed/20350930 http://dx.doi.org/10.1093/nar/gkq173

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