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Optimal design of parallel triplex forming oligonucleotides containing Twisted Intercalating Nucleic Acids—TINA

Twisted intercalating nucleic acid (TINA) is a novel intercalator and stabilizer of Hoogsteen type parallel triplex formations (PT). Specific design rules for position of TINA in triplex forming oligonucleotides (TFOs) have not previously been presented. We describe a complete collection of easy and...

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Detalles Bibliográficos
Autores principales:	Schneider, Uffe V., Mikkelsen, Nikolaj D., Jøhnk, Nina, Okkels, Limei M., Westh, Henrik, Lisby, Gorm
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910062/ https://www.ncbi.nlm.nih.gov/pubmed/20338879 http://dx.doi.org/10.1093/nar/gkq188

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