Leukocyte membrane bleb and pseudopod formation in hypertension

Leukocyte activation, including adhesion molecule expression, oxygen radical generation and, in animal studies, pseudopod formation, is a hallmark of hypertension. This study examined pseudopod and bleb formation and demonstrates that leukocytes from hypertensive individuals are more susceptible to...

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Autores principales: Edwards, Kate M., Sheu, Bryan, Hong, Suzi, Penn, Alexander H., Schmid-Schönbein, Geert W., Mills, Paul J
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910234/
https://www.ncbi.nlm.nih.gov/pubmed/20410916
http://dx.doi.org/10.1038/jhh.2010.41
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author Edwards, Kate M.
Sheu, Bryan
Hong, Suzi
Penn, Alexander H.
Schmid-Schönbein, Geert W.
Mills, Paul J
author_facet Edwards, Kate M.
Sheu, Bryan
Hong, Suzi
Penn, Alexander H.
Schmid-Schönbein, Geert W.
Mills, Paul J
author_sort Edwards, Kate M.
collection PubMed
description Leukocyte activation, including adhesion molecule expression, oxygen radical generation and, in animal studies, pseudopod formation, is a hallmark of hypertension. This study examined pseudopod and bleb formation and demonstrates that leukocytes from hypertensive individuals are more susceptible to produce membrane blebs than leukocytes from normotensive individuals. Bleb formation is likely indicative of apoptosis, thus this observation adds to previous observations of increased apoptosis in various tissues in hypertension.
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spelling pubmed-29102342011-04-01 Leukocyte membrane bleb and pseudopod formation in hypertension Edwards, Kate M. Sheu, Bryan Hong, Suzi Penn, Alexander H. Schmid-Schönbein, Geert W. Mills, Paul J J Hum Hypertens Article Leukocyte activation, including adhesion molecule expression, oxygen radical generation and, in animal studies, pseudopod formation, is a hallmark of hypertension. This study examined pseudopod and bleb formation and demonstrates that leukocytes from hypertensive individuals are more susceptible to produce membrane blebs than leukocytes from normotensive individuals. Bleb formation is likely indicative of apoptosis, thus this observation adds to previous observations of increased apoptosis in various tissues in hypertension. 2010-04-22 2010-10 /pmc/articles/PMC2910234/ /pubmed/20410916 http://dx.doi.org/10.1038/jhh.2010.41 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Edwards, Kate M.
Sheu, Bryan
Hong, Suzi
Penn, Alexander H.
Schmid-Schönbein, Geert W.
Mills, Paul J
Leukocyte membrane bleb and pseudopod formation in hypertension
title Leukocyte membrane bleb and pseudopod formation in hypertension
title_full Leukocyte membrane bleb and pseudopod formation in hypertension
title_fullStr Leukocyte membrane bleb and pseudopod formation in hypertension
title_full_unstemmed Leukocyte membrane bleb and pseudopod formation in hypertension
title_short Leukocyte membrane bleb and pseudopod formation in hypertension
title_sort leukocyte membrane bleb and pseudopod formation in hypertension
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910234/
https://www.ncbi.nlm.nih.gov/pubmed/20410916
http://dx.doi.org/10.1038/jhh.2010.41
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AT pennalexanderh leukocytemembraneblebandpseudopodformationinhypertension
AT schmidschonbeingeertw leukocytemembraneblebandpseudopodformationinhypertension
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