The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa

Pat proteins regulate the transition of mRNAs from a state that is translationally active to one that is repressed, committing targeted mRNAs to degradation. Pat proteins contain a conserved N-terminal sequence, a proline-rich region, a Mid domain and a C-terminal domain (Pat-C). We show that Pat-C...

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Detalles Bibliográficos
Autores principales: Braun, Joerg E, Tritschler, Felix, Haas, Gabrielle, Igreja, Cátia, Truffault, Vincent, Weichenrieder, Oliver, Izaurralde, Elisa
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910274/
https://www.ncbi.nlm.nih.gov/pubmed/20543818
http://dx.doi.org/10.1038/emboj.2010.124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910274/
https://www.ncbi.nlm.nih.gov/pubmed/20543818
http://dx.doi.org/10.1038/emboj.2010.124

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