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Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca(2+)-Release Channels/Ryanodine Receptors

Scorpion venoms are rich in ion channel-modifying peptides, which have proven to be invaluable probes of ion channel structure-function relationship. We previously isolated imperatoxin A (IpTxa), a 3.7 kDa peptide activator of Ca(2+)-release channels/ryanodine receptors (RyRs) [1,2,3] and founding m...

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Detalles Bibliográficos
Autores principales: Gurrola, Georgina B., Capes, E. Michelle, Zamudio, Fernando Z., Possani, Lourival D., Valdivia, Héctor H.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910439/
https://www.ncbi.nlm.nih.gov/pubmed/20668646
http://dx.doi.org/10.3390/ph3041093