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Inhibition of Methylglyoxal-Mediated Protein Modification in Glyoxalase I Overexpressing Mouse Lenses

Objective. Here we tested the role of Glo I in the prevention of advanced glycation end product (AGE) formation in transgenic mouse lenses. Methods. A transgenic animal line that expressed high levels of human Glo I in the lens was developed from the C57B6 mouse strain. The role of Glo I in the inhi...

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Detalles Bibliográficos
Autores principales:	Gangadhariah, Mahesha H., Mailankot, Maneesh, Reneker, Lixing, Nagaraj, Ram H.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910474/ https://www.ncbi.nlm.nih.gov/pubmed/20671953 http://dx.doi.org/10.1155/2010/274317

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