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Molecular Characterization of the Onset and Progression of Colitis in Inoculated Interleukin-10 Gene-Deficient Mice: A Role for PPARα

The interleukin-10 gene-deficient (Il10 (−/−)) mouse is a model of human inflammatory bowel disease and Ppara has been identified as one of the key genes involved in regulation of colitis in the bacterially inoculated Il10 (−/−) model. The aims were to (1) characterize colitis onset and progression...

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Detalles Bibliográficos
Autores principales: Knoch, Bianca, Barnett, Matthew P. G., Cooney, Janine, McNabb, Warren C., Barraclough, Diane, Laing, William, Zhu, Shuotun, Park, Zaneta A., MacLean, Paul, Knowles, Scott O., Roy, Nicole C.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910480/
https://www.ncbi.nlm.nih.gov/pubmed/20671959
http://dx.doi.org/10.1155/2010/621069