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Molecular Characterization of the Onset and Progression of Colitis in Inoculated Interleukin-10 Gene-Deficient Mice: A Role for PPARα
The interleukin-10 gene-deficient (Il10 (−/−)) mouse is a model of human inflammatory bowel disease and Ppara has been identified as one of the key genes involved in regulation of colitis in the bacterially inoculated Il10 (−/−) model. The aims were to (1) characterize colitis onset and progression...
Autores principales: | Knoch, Bianca, Barnett, Matthew P. G., Cooney, Janine, McNabb, Warren C., Barraclough, Diane, Laing, William, Zhu, Shuotun, Park, Zaneta A., MacLean, Paul, Knowles, Scott O., Roy, Nicole C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910480/ https://www.ncbi.nlm.nih.gov/pubmed/20671959 http://dx.doi.org/10.1155/2010/621069 |
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