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Shiga Toxin Increases Formation of Clathrin-Coated Pits through Syk Kinase
Clathrin-dependent endocytosis is a main entry mechanism for the glycolipid-binding Shiga toxin (Stx), although clathrin-independent pathways are also involved. Binding of Stx to its receptor Gb3 not only is essential for Stx retrograde transport to the endoplasmic reticulum and toxicity but also ac...
Autores principales: | Utskarpen, Audrun, Massol, Ramiro, van Deurs, Bo, Lauvrak, Silje Ugland, Kirchhausen, Tomas, Sandvig, Kirsten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910670/ https://www.ncbi.nlm.nih.gov/pubmed/20668539 http://dx.doi.org/10.1371/journal.pone.0010944 |
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