Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

BACKGROUND: Mutation analysis of KIT and PDGFRA genes in gastrointestinal stromal tumors is gaining increasing importance for prognosis of GISTs and for prediction of treatment response. Several groups have identified specific mutational subtypes in KIT exon 11 associated with an increased risk of m...

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Detalles Bibliográficos
Autores principales: Merkelbach-Bruse, Sabine, Dietmaier, Wolfgang, Füzesi, Laszlo, Gaumann, Andreas, Haller, Florian, Kitz, Julia, Krohn, Antje, Mechtersheimer, Gunhild, Penzel, Roland, Schildhaus, Hans-Ulrich, Schneider-Stock, Regine, Simon, Ronald, Wardelmann, Eva
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910708/
https://www.ncbi.nlm.nih.gov/pubmed/20598160
http://dx.doi.org/10.1186/1471-2350-11-106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910708/
https://www.ncbi.nlm.nih.gov/pubmed/20598160
http://dx.doi.org/10.1186/1471-2350-11-106

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