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Absence of Inhibin Alpha and Retinoblastoma Protein Leads to Early Sertoli Cell Dysfunction
Sertoli cells, the support cells of mammalian spermatogenesis, are regulated by a number of nuclear factors and express retinoblastoma (RB) tumor suppressor protein. We hypothesized that RB is an important mediator of Sertoli cell tumorigenesis in inhibin α knockout (Inha KO) mice. In our previous m...
Autores principales: | Nalam, Roopa L., Andreu-Vieyra, Claudia, Matzuk, Martin M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910728/ https://www.ncbi.nlm.nih.gov/pubmed/20676395 http://dx.doi.org/10.1371/journal.pone.0011797 |
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