Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse

OBJECTIVE: Previous studies showed that genetic deletion or pharmacological blockade of the receptor for advanced glycation end products (RAGE) prevents the early structural changes in the glomerulus associated with diabetic nephropathy. To overcome limitations of mouse models that lack the progress...

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Detalles Bibliográficos
Autores principales: Reiniger, Nina, Lau, Kai, McCalla, Daren, Eby, Bonnie, Cheng, Bin, Lu, Yan, Qu, Wu, Quadri, Nosirudeen, Ananthakrishnan, Radha, Furmansky, Maryana, Rosario, Rosa, Song, Fei, Rai, Vivek, Weinberg, Alan, Friedman, Richard, Ramasamy, Ravichandran, D'Agati, Vivette, Schmidt, Ann Marie
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911065/
https://www.ncbi.nlm.nih.gov/pubmed/20627935
http://dx.doi.org/10.2337/db09-1766

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