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Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

OBJECTIVE: Most knowledge on human β-cell cycle control derives from immunoblots of whole human islets, mixtures of β-cells and non-β-cells. We explored the presence, subcellular localization, and function of five early G1/S phase molecules—cyclins D1–3 and cdk 4 and 6—in the adult human β-cell. RES...

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Detalles Bibliográficos
Autores principales:	Fiaschi-Taesch, Nathalie M., Salim, Fatimah, Kleinberger, Jeffrey, Troxell, Ronnie, Cozar-Castellano, Irene, Selk, Karen, Cherok, Edward, Takane, Karen K., Scott, Donald K., Stewart, Andrew F.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911074/ https://www.ncbi.nlm.nih.gov/pubmed/20668294 http://dx.doi.org/10.2337/db09-1776

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