Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine

OBJECTIVE: Defects in insulin/IGF-1 signaling stimulate muscle protein loss by suppressing protein synthesis and increasing protein degradation. Since an herbal compound, berberine, lowers blood levels of glucose and lipids, we proposed that it would improve insulin/IGF-1 signaling, blocking muscle...

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Detalles Bibliográficos
Autores principales: Wang, Huiling, Liu, Dajun, Cao, Peirang, Lecker, Stewart, Hu, Zhaoyong
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911075/
https://www.ncbi.nlm.nih.gov/pubmed/20522589
http://dx.doi.org/10.2337/db10-0207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911075/
https://www.ncbi.nlm.nih.gov/pubmed/20522589
http://dx.doi.org/10.2337/db10-0207

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