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Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
BACKGROUND: In mammals, the dynamics of DNA methylation, in particular the regulated, active removal of cytosine methylation, has remained a mystery, partly due to the lack of appropriate model systems to study DNA demethylation. Previous work has largely focused on proliferating cell types that are...
Autores principales: | Klug, Maja, Heinz, Sven, Gebhard, Claudia, Schwarzfischer, Lucia, Krause, Stefan W, Andreesen, Reinhard, Rehli, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911111/ https://www.ncbi.nlm.nih.gov/pubmed/20565882 http://dx.doi.org/10.1186/gb-2010-11-6-r63 |
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