The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients

The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling axis plays a central role in cell proliferation, growth, and survival under physiological conditions. However, aberrant PI3K/Akt/mTOR signaling has been implicated in many human cancers, including acute myelo...

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Detalles Bibliográficos
Autores principales: Martelli, Alberto M., Evangelisti, Camilla, Chiarini, Francesca, McCubrey, James A.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911128/
https://www.ncbi.nlm.nih.gov/pubmed/20671809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911128/
https://www.ncbi.nlm.nih.gov/pubmed/20671809

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