Psychological Stress-Induced, IDO1-Dependent Tryptophan Catabolism: Implications on Immunosuppression in Mice and Humans

It is increasingly recognized that psychological stress influences inflammatory responses and mood. Here, we investigated whether psychological stress (combined acoustic and restraint stress) activates the tryptophan (Trp) catabolizing enzyme indoleamine 2,3-dioxygenase 1(IDO1) and thereby alters th...

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Detalles Bibliográficos
Autores principales: Kiank, Cornelia, Zeden, Jan-Philip, Drude, Solveig, Domanska, Grazyna, Fusch, Gerhard, Otten, Winfried, Schuett, Christine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911374/
https://www.ncbi.nlm.nih.gov/pubmed/20689575
http://dx.doi.org/10.1371/journal.pone.0011825

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