Breast cancer stromal fibroblasts promote the generation of CD44(+)CD24(- )cells through SDF-1/CXCR4 interaction

BACKGROUND: Breast cancer stem cells (BCSCs) have been recently identified in breast carcinoma as CD44(+)CD24(- )cells, which exclusively retain tumorigenic activity and display stem cell-like properties. Using a mammosphere culture technique, MCF7 mammosphere cells are found to enrich breast cancer...

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Detalles Bibliográficos
Autores principales: Huang, Mingzhu, Li, Yuqing, Zhang, Huanle, Nan, Feifei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911413/
https://www.ncbi.nlm.nih.gov/pubmed/20569497
http://dx.doi.org/10.1186/1756-9966-29-80

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