The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP(2)-binding peptide

BACKGROUND: The molecular basis for neutrophil recognition of chemotactic peptides is their binding to specific G-protein-coupled cell surface receptors (GPCRs). Human neutrophils express two pattern recognition GPCRs, FPR1 and FPR2, which belong to the family of formyl peptide receptors. The high d...

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Detalles Bibliográficos
Autores principales: Forsman, Huamei, Dahlgren, Claes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911415/
https://www.ncbi.nlm.nih.gov/pubmed/20602801
http://dx.doi.org/10.1186/1471-2121-11-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911415/
https://www.ncbi.nlm.nih.gov/pubmed/20602801
http://dx.doi.org/10.1186/1471-2121-11-52

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