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Local alignment of generalized k-base encoded DNA sequence

BACKGROUND: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however observe an encoded form of the sequence, rather than each DNA base individually. The encoded DNA sequence may contain tech...

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Detalles Bibliográficos
Autores principales: Homer, Nils, Nelson, Stanley F, Merriman, Barry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911458/
https://www.ncbi.nlm.nih.gov/pubmed/20576157
http://dx.doi.org/10.1186/1471-2105-11-347