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Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report

INTRODUCTION: The frequency of intra-orbital metastasis in systemic cancer is a controversial topic. Of all metastatic tumors to the orbit of the eye, breast carcinoma is considered to be the most prevalent. Orbital findings typically present themselves after the diagnosis of the primary tumor, with...

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Autores principales: Francone, Elisa, Murelli, Federica, Paroldi, Alessandro, Margarino, Cecilia, Friedman, Daniele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911468/
https://www.ncbi.nlm.nih.gov/pubmed/20633264
http://dx.doi.org/10.1186/1752-1947-4-211
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author Francone, Elisa
Murelli, Federica
Paroldi, Alessandro
Margarino, Cecilia
Friedman, Daniele
author_facet Francone, Elisa
Murelli, Federica
Paroldi, Alessandro
Margarino, Cecilia
Friedman, Daniele
author_sort Francone, Elisa
collection PubMed
description INTRODUCTION: The frequency of intra-orbital metastasis in systemic cancer is a controversial topic. Of all metastatic tumors to the orbit of the eye, breast carcinoma is considered to be the most prevalent. Orbital findings typically present themselves after the diagnosis of the primary tumor, with an average delay of three to six years. In spite of that, this study reports a case in which orbital manifestation was the initial symptom in breast carcinoma diagnosis. CASE PRESENTATION: A 66-year-old Italian Caucasian woman presented with a swelling located on the lower orbit of her right eye. CONCLUSIONS: Previous cases report orbital manifestations discovered secondary to breast cancer. This case demonstrates that orbital symptoms may be the primary presentation of the disease. Orbital metastasis originating from breast cancer predicts widespread metastatic disease in other organs. In the presence of an ambiguous infiltrative orbital process, diagnostic examination of the breast is recommended.
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spelling pubmed-29114682010-07-29 Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report Francone, Elisa Murelli, Federica Paroldi, Alessandro Margarino, Cecilia Friedman, Daniele J Med Case Reports Case Report INTRODUCTION: The frequency of intra-orbital metastasis in systemic cancer is a controversial topic. Of all metastatic tumors to the orbit of the eye, breast carcinoma is considered to be the most prevalent. Orbital findings typically present themselves after the diagnosis of the primary tumor, with an average delay of three to six years. In spite of that, this study reports a case in which orbital manifestation was the initial symptom in breast carcinoma diagnosis. CASE PRESENTATION: A 66-year-old Italian Caucasian woman presented with a swelling located on the lower orbit of her right eye. CONCLUSIONS: Previous cases report orbital manifestations discovered secondary to breast cancer. This case demonstrates that orbital symptoms may be the primary presentation of the disease. Orbital metastasis originating from breast cancer predicts widespread metastatic disease in other organs. In the presence of an ambiguous infiltrative orbital process, diagnostic examination of the breast is recommended. BioMed Central 2010-07-15 /pmc/articles/PMC2911468/ /pubmed/20633264 http://dx.doi.org/10.1186/1752-1947-4-211 Text en Copyright ©2010 Francone et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Francone, Elisa
Murelli, Federica
Paroldi, Alessandro
Margarino, Cecilia
Friedman, Daniele
Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title_full Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title_fullStr Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title_full_unstemmed Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title_short Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
title_sort orbital swelling as a first symptom in breast carcinoma diagnosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911468/
https://www.ncbi.nlm.nih.gov/pubmed/20633264
http://dx.doi.org/10.1186/1752-1947-4-211
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