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Design, Synthesis, and Analysis of Minor Groove Binder Pyrrolepolyamide-2′-Deoxyguanosine Hybrids

Pyrrolepolyamide-2′-deoxyguanosine hybrids (Hybrid 2 and Hybrid 3) incorporating the 3-aminopropionyl or 3-aminopropyl linker were designed and synthesized on the basis of previously reported results of a pyrrolepolyamide-adenosine hybrid (Hybrid 1). Evaluation of the DNA binding sequence selectivit...

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Detalles Bibliográficos
Autores principales:	Kawashima, Etsuko, Ohba, Yusuke, Terui, Yusuke, Kamaike, Kazuo
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911594/ https://www.ncbi.nlm.nih.gov/pubmed/20700414 http://dx.doi.org/10.4061/2010/235240

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