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Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy
Background. Cervicocephalic arterial dissection (CCAD) is rare in the postpartum period. To our knowledge this is the first reported case of postpartum angiopathy (PPA) presenting with ischemic stroke due to intracranial arterial dissection. Case. A 41-year-old woman presented with blurred vision, h...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911601/ https://www.ncbi.nlm.nih.gov/pubmed/20700423 http://dx.doi.org/10.4061/2010/320627 |
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author | McKinney, James S. Messé, Steven R. Pukenas, Bryan A. Satti, Sudhakar R. Weigele, John B. Hurst, Robert W. Levine, Joshua M. Kasner, Scott E. Sansing, Lauren H. |
author_facet | McKinney, James S. Messé, Steven R. Pukenas, Bryan A. Satti, Sudhakar R. Weigele, John B. Hurst, Robert W. Levine, Joshua M. Kasner, Scott E. Sansing, Lauren H. |
author_sort | McKinney, James S. |
collection | PubMed |
description | Background. Cervicocephalic arterial dissection (CCAD) is rare in the postpartum period. To our knowledge this is the first reported case of postpartum angiopathy (PPA) presenting with ischemic stroke due to intracranial arterial dissection. Case. A 41-year-old woman presented with blurred vision, headache, and generalized seizures 5 days after delivering twins. She was treated with magnesium for eclampsia. MRI identified multiple posterior circulation infarcts. Angiography identified a complex dissection extending from both intradural vertebral arteries, through the basilar artery, and into both posterior cerebral arteries. Multiple segments of arterial dilatation and narrowing consistent with PPA were present. Xenon enhanced CT (Xe-CT) showed reduced regional cerebral blood flow that is improved with elevation in blood pressure. Conclusion. Intracranial vertebrobasilar dissection causing stroke is a rare complication of pregnancy. Eclampsia and PPA may play a role in its pathogenesis. Blood pressure management may be tailored using quantitative blood flow studies, such as Xe-CT. |
format | Text |
id | pubmed-2911601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-29116012010-08-10 Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy McKinney, James S. Messé, Steven R. Pukenas, Bryan A. Satti, Sudhakar R. Weigele, John B. Hurst, Robert W. Levine, Joshua M. Kasner, Scott E. Sansing, Lauren H. Stroke Res Treat Case Report Background. Cervicocephalic arterial dissection (CCAD) is rare in the postpartum period. To our knowledge this is the first reported case of postpartum angiopathy (PPA) presenting with ischemic stroke due to intracranial arterial dissection. Case. A 41-year-old woman presented with blurred vision, headache, and generalized seizures 5 days after delivering twins. She was treated with magnesium for eclampsia. MRI identified multiple posterior circulation infarcts. Angiography identified a complex dissection extending from both intradural vertebral arteries, through the basilar artery, and into both posterior cerebral arteries. Multiple segments of arterial dilatation and narrowing consistent with PPA were present. Xenon enhanced CT (Xe-CT) showed reduced regional cerebral blood flow that is improved with elevation in blood pressure. Conclusion. Intracranial vertebrobasilar dissection causing stroke is a rare complication of pregnancy. Eclampsia and PPA may play a role in its pathogenesis. Blood pressure management may be tailored using quantitative blood flow studies, such as Xe-CT. SAGE-Hindawi Access to Research 2009-09-01 /pmc/articles/PMC2911601/ /pubmed/20700423 http://dx.doi.org/10.4061/2010/320627 Text en Copyright © 2010 James S. McKinney et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report McKinney, James S. Messé, Steven R. Pukenas, Bryan A. Satti, Sudhakar R. Weigele, John B. Hurst, Robert W. Levine, Joshua M. Kasner, Scott E. Sansing, Lauren H. Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title | Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title_full | Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title_fullStr | Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title_full_unstemmed | Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title_short | Intracranial Vertebrobasilar Artery Dissection Associated with Postpartum Angiopathy |
title_sort | intracranial vertebrobasilar artery dissection associated with postpartum angiopathy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911601/ https://www.ncbi.nlm.nih.gov/pubmed/20700423 http://dx.doi.org/10.4061/2010/320627 |
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