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Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes

C-myc and Bcl2 are well characterized oncogenes that are capable of forming G-quadruplex structures. Promoter regions of C-myc and Bcl2 forming G-quadruplex structures are chemically synthesized and G-quadruplex structure is formed in presence of 100 mM potassium ion. Three different porphyrin drugs...

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Detalles Bibliográficos
Autores principales:	Nagesh, Narayana, Sharma, Varun K., Ganesh Kumar, A., Lewis, Edwin A.
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911617/ https://www.ncbi.nlm.nih.gov/pubmed/20700417 http://dx.doi.org/10.4061/2010/146418

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