Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A

Here we provide evidence in support of an inherent role for Arpc1b, a component of the Arp2/3 complex, in regulation of mitosis and demonstrate that its depletion inhibits Aurora A activation at the centrosome and impairs the ability of mammalian cells to enter mitosis. We discovered that Arpc1b col...

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Detalles Bibliográficos
Autores principales: Molli, Poonam R., Li, Da-Qiang, Bagheri-Yarmand, Rozita, Pakala, Suresh B., Katayama, Hiroshi, Sen, Subrata, Iyer, Jyoti, Chernoff, Jonathan, Tsai, Ming-Ying, Nair, Sujit S., Kumar, Rakesh
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911675/
https://www.ncbi.nlm.nih.gov/pubmed/20603326
http://dx.doi.org/10.1083/jcb.200908050

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