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The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction
INTRODUCTION: The impact of pro-inflammatory cytokines on neuroinflammation and cognitive function after lipopolysaccharide (LPS) challenge remains elusive. Herein we provide evidence that there is a temporal correlation between high-mobility group box 1 (HMGB-1), microglial activation, and cognitiv...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911722/ https://www.ncbi.nlm.nih.gov/pubmed/20470406 http://dx.doi.org/10.1186/cc9019 |