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BrainTrap: a database of 3D protein expression patterns in the Drosophila brain
Protein-trap strains of Drosophila melanogaster provide a very useful tool for examining the 3D-expression patterns of proteins and purification of protein complexes. Here we present BrainTrap, available at http://fruitfly.inf.ed.ac.uk/braintrap, an online database of 3D confocal datasets showing re...
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911840/ https://www.ncbi.nlm.nih.gov/pubmed/20624714 http://dx.doi.org/10.1093/database/baq005 |
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author | Knowles-Barley, Seymour Longair, Mark Armstrong, J Douglas |
author_facet | Knowles-Barley, Seymour Longair, Mark Armstrong, J Douglas |
author_sort | Knowles-Barley, Seymour |
collection | PubMed |
description | Protein-trap strains of Drosophila melanogaster provide a very useful tool for examining the 3D-expression patterns of proteins and purification of protein complexes. Here we present BrainTrap, available at http://fruitfly.inf.ed.ac.uk/braintrap, an online database of 3D confocal datasets showing reporter gene expression and protein localization in the adult brain of Drosophila. Full size images throughout the volume of the entire brain can be viewed interactively in a web browser. The database includes searchable annotations linked to the FlyBase Drosophila anatomy ontology. Anatomical search criteria can be specified using automatic completion and a hierarchical browser for the ontology. The provenance of all annotation is retained and the location where the annotator made the conclusion can be highlighted. Database URL: http://fruitfly.inf.ed.ac.uk/braintrap |
format | Text |
id | pubmed-2911840 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-29118402010-07-30 BrainTrap: a database of 3D protein expression patterns in the Drosophila brain Knowles-Barley, Seymour Longair, Mark Armstrong, J Douglas Database (Oxford) Original Article Protein-trap strains of Drosophila melanogaster provide a very useful tool for examining the 3D-expression patterns of proteins and purification of protein complexes. Here we present BrainTrap, available at http://fruitfly.inf.ed.ac.uk/braintrap, an online database of 3D confocal datasets showing reporter gene expression and protein localization in the adult brain of Drosophila. Full size images throughout the volume of the entire brain can be viewed interactively in a web browser. The database includes searchable annotations linked to the FlyBase Drosophila anatomy ontology. Anatomical search criteria can be specified using automatic completion and a hierarchical browser for the ontology. The provenance of all annotation is retained and the location where the annotator made the conclusion can be highlighted. Database URL: http://fruitfly.inf.ed.ac.uk/braintrap Oxford University Press 2010-03-24 /pmc/articles/PMC2911840/ /pubmed/20624714 http://dx.doi.org/10.1093/database/baq005 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Knowles-Barley, Seymour Longair, Mark Armstrong, J Douglas BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title | BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title_full | BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title_fullStr | BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title_full_unstemmed | BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title_short | BrainTrap: a database of 3D protein expression patterns in the Drosophila brain |
title_sort | braintrap: a database of 3d protein expression patterns in the drosophila brain |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911840/ https://www.ncbi.nlm.nih.gov/pubmed/20624714 http://dx.doi.org/10.1093/database/baq005 |
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