Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

INTRODUCTION: Rheumatoid arthritis synovial fibroblasts (RASF) are key players in synovial pathophysiology and are therefore examined extensively in various experimental approaches. We evaluated, whether passaging during culture and freezing has effects on gene expression and cell proliferation. MET...

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Detalles Bibliográficos
Autores principales: Neumann, Elena, Riepl, Birgit, Knedla, Anette, Lefèvre, Stephanie, Tarner, Ingo H, Grifka, Joachim, Steinmeyer, Jurgen, Schölmerich, Jurgen, Gay, Steffen, Müller-Ladner, Ulf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911867/
https://www.ncbi.nlm.nih.gov/pubmed/20462438
http://dx.doi.org/10.1186/ar3010

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