Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis

INTRODUCTION: The purpose of this study was to evaluate the effects of L-4F, an apolipoprotein A-1 mimetic peptide, alone or with pravastatin, in apoE(-/-)Fas(-/-)C57BL/6 mice that spontaneously develop immunoglobulin G (IgG) autoantibodies, glomerulonephritis, osteopenia, and atherosclerotic lesion...

Descripción completa

Detalles Bibliográficos
Autores principales: Woo, Jennifer MP, Lin, Zhuofeng, Navab, Mohamad, Van Dyck, Casey, Trejo-Lopez, Yvette, Woo, Krystal MT, Li, Hongyun, Castellani, Lawrence W, Wang, Xuping, Iikuni, Noriko, Rullo, Ornella J, Wu, Hui, La Cava, Antonio, Fogelman, Alan M, Lusis, Aldons J, Tsao, Betty P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911877/
https://www.ncbi.nlm.nih.gov/pubmed/20482780
http://dx.doi.org/10.1186/ar3020

Ejemplares similares

Ejemplares similares